Round-window delivery of neurotrophin 3 regenerates cochlear synapses after acoustic overexposure
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چکیده
منابع مشابه
Round window electrocochleography before and after cochlear implant electrode insertion.
OBJECTIVE/HYPOTHESIS Previous reports have documented the feasibility of utilizing electrocochleographic (ECoG) responses to acoustic signals to assess trauma caused during cochlear implantation. The hypothesis is that intraoperative round window ECoG before and after electrode insertion will help predict postoperative hearing preservation outcomes in cochlear implant recipients. STUDY DESIGN...
متن کاملComparison of the Pediatric Cochlear Implantation Using Round Window and Cochleostomy
Introduction: Cochlear implantation (CI) is now regarded as a standard treatment for children with severe to profound sensor neural hearing loss. This study aimed to compare the efficacy of the round window approach (RWA) and standard cochleostomy approach (SCA) in the preservation of residual hearing after CI in pediatric patients. Materials and Methods: This double-blind ran...
متن کاملModelling the effect of round window stiffness on residual hearing after cochlear implantation
Preservation of residual hearing after cochlear implantation is now considered an important goal of surgery. However, studies indicate an average post-operative hearing loss of around 20 dB at low frequencies. One factor which may contribute to post-operative hearing loss, but which has received little attention in the literature to date, is the increased stiffness of the round window, due to t...
متن کاملIntratympanic and Round-Window Drug Therapy: Effect on Cochlear Tinnitus.
Tinnitus is a common symptom for which few existing therapeutic approaches can produce reliable reduction or elimination. Chemical perfusion involves the delivery of medication directly into the inner ear via the round-window membrane. This report discusses the use of dexamethasone or gentamicin in 20 individuals who had inner ear diseases in which disturbing cochlear tinnitus was one of the sy...
متن کاملResidual hearing preservation after cochlear implantation via round window or cochleostomy approach.
OBJECTIVES/HYPOTHESIS The purpose of the study was to investigate whether cochlear implantation using the round window approach provided better preservation of residual hearing than the cochleostomy approach. STUDY DESIGN Case-control study. METHODS We designed a case-control study including 40 patients from a tertiary referral center who underwent cochlear implantation surgeries using devi...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep24907